THE 2-MINUTE RULE FOR DIIDROCODEINA IN ITALIA

Hepatic Impairment Following oral administration of an individual four mg dose (two mg hydromorphone instant-launch tablets), imply exposure to hydromorphone (Cmax and AUC∞) is enhanced four-fold in individuals with reasonable (Boy or girl-Pugh Group B) hepatic impairment compared with topics with normal hepatic perform. Resulting from amplified